1. Cardiovascular biology

2. Cell and developmental biology

3. Genetic and epigenetic regulation of gene expression

4. Genome stability, aging and cancer

Since 2020 Member of the Structure and Development Committee of the Medical Faculty Mannheim

Since 2020 Member of the Research Committee of the Medical Faculty Mannheim

Since 2017 Member of the German Center for Cardiovascular Disease (DZHK) of BMBF

2016 Peter Hans Hofschneider Endowed Professorship Award from Stiftung experimentelle Biomedizin.

2012 Member of the German Center for Lung Research of BMBF (DZL).

2012 - 2016 Co-coordinator of Area A (“Stem/progenitor Cells in Development, Repair and Therapy”) of the Excellence Cluster Cardio-Pulmonary System (ECCPS).

2010 - 2011 Co-coordinator of Project Area K (“Developmental Biology”) of the Excellence Cluster Cardio-Pulmonary System (ECCPS).

2007 - 2012 Emmy Noether Independent Junior Group Leader Award from the German Research Foundation (DFG).

• Wang Y, Elsherbiny A, Kessler L, Cordero J, Shi H, Serke H, Lityagina O, Trogisch FA, Mohammadi MM, El-Battrawy I, Backs J, Wieland T, Heineke J, Dobreva G. “Lamin A/C-dependent chromatin architecture safeguards naïve pluripotency to prevent aberrant cardiovascular cell fate and function.” Nat Commun. 2022 Nov 4;13(1):6663

• Gao R, Liang X, Cheedipudi S, Cordero J, Jiang X, Zhang Q, Caputo L, Günther S, Kuenne C, Ren Y, Bhattacharya S, Yuan X, Barreto G, Chen Y, Braun T, Evans SM, Sun Y, Dobreva G. “Pioneering function of Isl1 in epigenetic control of cardiomyocyte cell fate.” Cell Research 2019, 29(6):486-501.

• Jia Y, Vong J, Asafova A, Garvalov BK, Caputo L, Cordero J, Singh A, Boettger T, Günther S, Fink L, Acker T, Barreto G, Seeger W, Braun T, Savai R, Dobreva G. “Lamin B1 loss promotes lung cancer development and metastasis by epigenetic derepression of RET.” J Exp Med 2019, 216(6):1377-1395.

• Caputo L, Witzel HR, Kolovos P, Cheedipudi S, Looso M, Mylona A, van IJcken WF, Laugwitz KL, Evans SM, Braun T, Soler E, Grosveld F, Dobreva G. “The Isl1/Ldb1 Complex Orchestrates Genome-wide Chromatin Organization to Instruct Differentiation of Multipotent Cardiac Progenitors.” Cell Stem Cell 2015, 17(3):287-99.

• Witzel H, Jungblut B, Choe CP, Crump JG, Braun T, Dobreva G. “The LIM protein Ajuba restricts the second heart field progenitor pool by regulating Isl1 activity” Dev Cell 2012, 23(1):58-70.