Dr. Mirko Völkers

Assistenzarzt (Klinik für Kardiologie, Angiologie, Pneumologie)

Arbeitsgruppenleiter (Molecular Biology of Cell Growth)

Im Neuenheimer Feld 410, 69120 Heidelberg

+49-6221-56-38029

mirko.voelkers@med.uni-heidelberg.de

  • mRNA biology in cardiac homeostasis and disease, RNA-binding proteins, mTOR kinase signaling, cardiometabolic disease, epitranscriptome, novel sequencing approaches

  • 2021 Arthur-Weber Award from the German Cardiac Society

    2015 Emmy Noether Junior Research Group Leader (DFG), Medical Faculty Heidelberg, Heidelberg University

    2010 Adumed- Research Award

    2008 Joachim Siebeneicher Prize, University Heidelberg

  • 1) Riechert E, Kmietczyk V, Stein F, Schwarzl T, Sekaran T, Jürgensen L, Kamuf-Schenk V, Varma E, Hofmann C, Rettel M, Martin J, Ramirez-Pedrazza M, Fernandez M, Méndez R, Katus HA, Hentze MWM & Völkers M: Identification of dynamic RNA-binding proteins uncovers a Cpeb4-controlled regulatory cascade during pathological cell growth of cardiomyocytes. Cell Rep 35:109100, 2021

    2) Gorska, AA, Sandmann C, Riechert E, Hofmann C, Malovrh E, Kmietczyk E, Ölschläger J, Jürgensen L, Kamuf-Schenk V, Stroh C, Furkel J, Konstandin MH, Sticht C, Boileau E, Dieterich C, Frey N, Katus HA, Doroudgar S & Völkers M: Muscle-specific translational control of Cand2 by mTORC1 regulates adverse cardiac remodeling. EMBO Rep 22: e52170, 2021

    3) Sanlialp A, Schumacher D, Kiper L, Varma E, Riechert E, Ho TC, Hofmann C, Kmietczyk V, Zimmermann F, Wirth A, Gorska AA, Burghaus J, Camacho Londoño JE, Katus HA, Doroudgar S, Freichel M, Völkers M. Saraf-dependent Activation of mTORC1 Regulates Cardiac Growth. J Mol Cell Cardiol 141:30-42, 2020

    4) Doroudgar S, Hofmann C, Boileau E, Malone B, Riechert E, Gorska AA, Jakobi T, Sandmann S, Jürgensen L, Kmietczyk V, Malovrh E, Burghaus J, Rettel M, Stein F, Younesi F, Friedrich UA, Mauz V, Backs J, Kramer G, Katus HA, Dieterich C, Völkers M. Monitoring cell type-specific gene expression using ribosomal sequencing in vivo during cardiac hemodynamic stress. Circ Res 125:431–448, 2019

    5) Kmietczyk V, Riechert R, Kalinski L, Boileau E, Malovrh E, Malone B, Gorska A, Hofmann C, Varma E, Jürgensen L, Kamuf-Schenk V, Altmüller J, Tappu R, Busch M, Most P, Katus HA, Dieterich C, Völkers M. m6A-mRNA methylation regulates cardiac gene expression and cellular growth. Life Sci. Alliance 2, e201800233 (2019).