Prof. Dr. Med.

Florian Leuschner

Projects:

Department of Cardiology, Angiology and Pneumology
University Hospital Heidelberg, Medical Faculty Heidelberg Heidelberg University
Germany
Im Neuenheimer Feld 410
69120 Heidelberg

Phone: +49-6221-56-8676

Email: [email protected]

Research Interests

Cardiac inflammation, myocardial infarction, heart failure, cardiocrine signaling, development of immunomodulating and anti-fibrotic treatment approaches.

Selected Coordinating Functions and Awards

2025

Speaker of the DZHK Focus Area “Immunocardiology”

2025

Scientific coordinator of the Advanced Clinician Scientist Program (funded by the BMBF) of Medical Faculty Heidelberg (MFHD)

2022

Arthur Weber Price of the German Cardiac Society (DGK)

2021

European Coordinator Leducq Network “The Inflammatory-Fibrosis Axis in Ischemic Heart Failure”

2021

Albert Fraenkel Price of the DGK

2020

Wilhelm P. Winterstein-Award of the German Heart Research Foundation

2018

Heisenberg Professorship “Immunocardiology” (W3 Full Professorship), University of Heidelberg

2016

Science Award Walter Siegenthaler Society

2015

Member and Speaker of the Junior Research Group of the Federal Ministry of Education and Research (BMBF, DeCaRe Consortium)

2013

Member/ Principal Investigator of the German Centre for Cardiovascular Research (DZHK, Partner Site HD/MA)

CRC1550 Related Publications

2025

Spatial multi-omics of acute myocardial infarction reveals a novel mode of immune cell infiltration

Wünnemann, F.*, Sicklinger, F.*, Bestak, K., Nimo, J., Thiemann, T., Amrute, J., Nordbeck, M., Hartmann, N., Ibarra-Arellano, M. A., Tanevski, J., Heine, C., Frey, N., Lavine, K. J., Coscia, F., Saez-Rodriguez, J., Leuschner, F.*, & Schapiro, D*. *equal contribution.

Nature CVR. 4, 1345–1362. 2025.

2025

High-throughput echocardiography-guided induction of myocardial ischemia/reperfusion in mice

Sicklinger F, Hartmann N, Kovacs A, Weinheimer C, Nigro J, Thiemann T, Amrute J, Schumacher D, Kornardt M, Wienecke LM, Rompel L, Fischer J, Bachman J, Bedard O, Das S, Kuhn TC, Völkers M, Brandes RP, Kramann R, Rosenthal N, Frey N, Lavine KJ, Leuschner F.

Circ Res. 136:1099–1109, 2025.

2024

Single-cell transcriptomics reveal distinctive patterns of fibroblast activation in heart failure with preserved ejection fraction

Lanzer, J. D., Wienecke, L. M., Ramirez Flores, R. O., Zylla, M. M., Kley, C., Hartmann, N., Sicklinger, F., Schultz, J. H., Frey, N., Saez-Rodriguez, J., & Leuschner, F.

Basic Res Cardiol. 119(6), 1001-1028. 2024.

2023

Translational control of Ybx1 expression regulates cardiac function in response to pressure overload in vivo

Varma, E., J. Burghaus, T. Schwarzl, T. Sekaran, P. Gupta, A.A. Gorska, C. Hofmann, C. Stroh, L. Jürgensen, V. Kamuf-Schenk, X.Li, R. Medert, F. Leuschner, V. Kmietczyk, H.A. Katus, M.W. Hentze, N. Frey and M. Völkers.

Basic Res Cardiol. 118:25, 2023.