© UKHD
Prof. Dr.

Johannes Backs

Projects:

Institute of Experimental Cardiology
Medical Faculty, Heidelberg University
Heidelberg, Germany – Eppelheimer Strasse 8
69115 Heidelberg

Research Interests

Epigenetic regulation of cardiac homeostasis and disease, histone deacetylases, calcium-dependent signaling, cardiometabolic disease, disease modelling, genetic engineering

Selected Coordinating Functions and Awards

2022
Spokesperson of the CRC 1550 ‘Molecular Circuits of Heart Disease’
2021
Coordinator of Innovation campus Region Rhine-Neckar with focus on cardiovascular cooperation and translation at Heidelberg University by MWK Baden-Württemberg
2021
Faculty Member of Molecular Medicine Partnership Unit of EMBL and Medical Faculty Heidelberg (MMPU)
2020
Member of the DFG study group (FK 205)
2019
Elected Vice-Chair for the Gordon Research Conference (GRC) on ‘Epigenetic Regulation of Cardiovascular Disease’ in 2023 (Chair in 2025)
2019
Speaker of the German Center of Cardiovascular Research (DZHK) partner site Heidelberg/Mannheim
2017
Arthur-Weber Award from the German Cardiac Society
2016
Outstanding Investigator Award from the International Society of Heart Research
2015
Outstanding Early Investigator Award from the Basic Cardiovascular Science Council, American Heart Association
2007
Emmy Noether Junior Research Group Leader (DFG), Medical Faculty Heidelberg, Heidelberg University

CRC1550 Related Publications

2024

Transverse aortic constriction multi-omics analysis uncovers pathophysiological cardiac molecular mechanisms

Gjerga E, Dewenter M, Britto-Borges T, Grosso J, Stein F, Eschenbach J, Rettel M, Backs J & Dieterich C.

Oxford 2024

2025

Mitochondrial NNT Promotes Diastolic Dysfunction in Cardiometabolic HFpEF

Pepin, M. E., Konrad, P. J. M., Nazir, S., Bazgir, F., Maack, C., Nickel, A., Gorman, J., Hohl, M., Schreiter, F., Dewenter, M., de Britto Chaves Filho, A., Schulze, A., Karlstaedt, A., Frey, N., Seidman, C., Seidman, J. & Backs, J.

Circ Res. 136:1564-78, 2025