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© UKHD
Prof. Dr. Med.

Florian Leuschner

Projects:

B06

Department of Cardiology, Angiology and Pneumology
University Hospital Heidelberg, Medical Faculty Heidelberg Heidelberg University
Germany
Im Neuenheimer Feld 410
69120 Heidelberg

Phone:  +49-6221-56-8676
Email:  [email protected]
Website
PubMed Publications

Research Interests

Cardiac inflammation, myocardial infarction, heart failure, cardiocrine signaling, development of immunomodulating and anti-fibrotic treatment approaches.

Selected Coordinating Functions and Awards

2025
Speaker of the DZHK Focus Area “Immunocardiology”
2025
Scientific coordinator of the Advanced Clinician Scientist Program (funded by the BMBF) of Medical Faculty Heidelberg (MFHD)
2022
Arthur Weber Price of the German Cardiac Society (DGK)
2021
European Coordinator Leducq Network “The Inflammatory-Fibrosis Axis in Ischemic Heart Failure”
2021
Albert Fraenkel Price of the DGK
2020
Wilhelm P. Winterstein-Award of the German Heart Research Foundation
2018
Heisenberg Professorship “Immunocardiology” (W3 Full Professorship), University of Heidelberg
2016
Science Award Walter Siegenthaler Society
2015
Member and Speaker of the Junior Research Group of the Federal Ministry of Education and Research (BMBF, DeCaRe Consortium)
2013
Member/ Principal Investigator of the German Centre for Cardiovascular Research (DZHK, Partner Site HD/MA)

CRC1550 Related Publications

2025

High-throughput echocardiography-guided induction of myocardial ischemia/reperfusion in mice

Sicklinger F, Hartmann N, Kovacs A, Weinheimer C, Nigro J, Thiemann T, Amrute J, Schumacher D, Kornardt M, Wienecke LM, Rompel L, Fischer J, Bachman J, Bedard O, Das S, Kuhn TC, Völkers M, Brandes RP, Kramann R, Rosenthal N, Frey N, Lavine KJ, Leuschner F.

Circ Res. 136:1099–1109, 2025.

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2025

Spatial multi-omics of acute myocardial infarction reveals a novel mode of immune cell infiltration

Wünnemann, F.*, Sicklinger, F.*, Bestak, K., Nimo, J., Thiemann, T., Amrute, J., Nordbeck, M., Hartmann, N., Ibarra-Arellano, M. A., Tanevski, J., Heine, C., Frey, N., Lavine, K. J., Coscia, F., Saez-Rodriguez, J., Leuschner, F.*, & Schapiro, D*. *equal contribution.

Nature CVR. 4, 1345–1362. 2025.

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2024

Single-cell transcriptomics reveal distinctive patterns of fibroblast activation in heart failure with preserved ejection fraction

Lanzer, J. D., Wienecke, L. M., Ramirez Flores, R. O., Zylla, M. M., Kley, C., Hartmann, N., Sicklinger, F., Schultz, J. H., Frey, N., Saez-Rodriguez, J., & Leuschner, F.

Basic Res Cardiol. 119(6), 1001-1028. 2024.

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2023

Translational control of Ybx1 expression regulates cardiac function in response to pressure overload in vivo

Varma, E., J. Burghaus, T. Schwarzl, T. Sekaran, P. Gupta, A.A. Gorska, C. Hofmann, C. Stroh, L. Jürgensen, V. Kamuf-Schenk, X.Li, R. Medert, F. Leuschner, V. Kmietczyk, H.A. Katus, M.W. Hentze, N. Frey and M. Völkers.

Basic Res Cardiol. 118:25, 2023.

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