Prof. Dr.

Mirko Völkers

Projects:

Professor and group leader
Department of Cardiology, Angiology and Pneumology
University Hospital Heidelberg, Medical Faculty Heidelberg,
Heidelberg University
Germany
Im Neuenheimer Feld 410
69120 Heidelberg

Research Interests

mRNA biology in cardiac homeostasis and disease, RNA-binding proteins, mTOR kinase signaling, cardiometabolic disease, epitranscriptome, novel sequencing approaches.

Selected Coordinating Functions and Awards

2024
Professor for mRNA metabolism, Heisenberg, Germany
2023
Heisenberg Program, DFG
2021
Plus3 Program Leader, Boehringer Ingelheim Foundation, Germany
2021
Arthur Weber Price, German Cardiac Society, Germany
2015
Emmy Noether Junior Research Group Leader (DFG), Medical Faculty Heidelberg, Heidelberg University, Germany
2010
Adumed Research Price, Adumed Foundation, Germany
2008
Joachim Siebeneicher Doctoral Thesis Award, University Heidelberg, Germany

CRC1550 Related Publications

2021

Identification of dynamic RNA-binding proteins uncovers a Cpeb4-controlled regulatory cascade during pathological cell growth of cardiomyocytes

Riechert E, Kmietczyk V, Stein F, Schwarzl T, Sekaran T, Jürgensen L, Kamuf-Schenk V, Varma E, Hofmann C, Rettel M, Martin J, Ramirez-Pedrazza M, Fernandez M, Méndez R, Katus HA, Hentze MW, Völkers M

Cell Reports. 11;35(6):109100, 2021.

2025

Cell Type-Specific Secretome Analysis Reveals Liver-Heart Crosstalk in HFpEF

Schütte JP, Markus N, Grein S, Kamuf-Schenk V, Stroh C, Rettel M, Stein F, Fischer J, Löwenthal Z, Leiner J, Wang BH, Kaye DM, Zylla MM, Frey N, Völkers M

Circ Res. 2025 May 23;136(11):1516-1518.

doi: 10.1161/CIRCRESAHA.125.326264.

2023

Ythdf2 regulates cardiac remodeling through its mRNA target transcripts

Kmietczyk V, Oelschlager J, Gupta P, Varma E, Hartl S, Furkel J, Konstandin M, Marx A, Loewenthal Z, Kamuf-Schenk V, Jurgensen L, Stroh C, Gorska A, Martin-Garrido A, Heineke J, Jakobi T, Frey N & Volkers M

J Mol Cell Cardiol. 181:57-66, 2023.

2024

Transient inhibition of translation improves cardiac function after ischemia/reperfusion by attenuating the inflammatory response

Hofmann C, Serafin A, Schwerdt OM, Fischer J, Sicklinger F, Younesi FS, Byrne NJ, Meyer IS, Malovrh E, Sandmann C, Jürgensen L, Kampf-Schenk V, Stroh C, Löwenthal Z, Finke D, Boileau E, Beisaw A, Bugger H, Bettel M, Stein F, Katus HA, Jakobi T, Frey N, Leuschner F, Völkers M

Circulation 150:1248-67, 2024

 

2023

Translational control of Ybx1 expression regulates cardiac function in response to pressure overload in vivo

Varma, E., J. Burghaus, T. Schwarzl, T. Sekaran, P. Gupta, A.A. Gorska, C. Hofmann, C. Stroh, L. Jürgensen, V. Kamuf-Schenk, X.Li, R. Medert, F. Leuschner, V. Kmietczyk, H.A. Katus, M.W. Hentze, N. Frey and M. Völkers.

Basic Res Cardiol. 118:25, 2023