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Prof. Dr.

Ralf Gilsbach

Projects:

A02

Deputy Director of the Institute of Experimental Cardiology
Medical Faculty, Heidelberg University
Germany
Eppelheimer Str. 8
69115 Heidelberg

Phone:  +49-6221-56-7674
Email:  ralf.gilsbach@uni-heidelberg.de
Website

Research Interests

Transcriptional control and spatial chromatin organization in cardiac cells in development and disease, functional genomics, data sciences.

Selected Coordinating Functions and Awards

2022
PI of the CRC 1550 ‘Molecular Circuits of Heart Disease’
2022
DZHK and full Professor at the University of Heidelberg
2021 – 2022
Faculty Member of the International Max Planck Research School for Molecular Organ Biology, Bad Nauheim
2019 – 2022
Associate Professor for Cardiac Regulation at the Center of Physiology, Goethe-University Frankfurt
2020 - 2025
PI of the CRC 1425 ‘ScarCare’
2020
Guido Tarrone Award der Heart Failure Association of the European Society of Cardiology

CRC1550 Related Publications

PubMed Publications
2024

In Vivo Silencing of Regulatory Elements Using a Single AAV-CRISPRi Vector

Laurette P, Cao C, Ramanujam D, Schwaderer M, Lueneburg T, Kuss S, Weiss L, Dilshat R, Furlong EEM, Rezende F, Engelhardt S & Gilsbach R.

Circ Res. 134:223-5, 2024.

view publication
2026

Chamber-Specific Chromatin Architecture Guides Functional Interpretation of Disease-Associated Cis-Regulatory Elements in Human Cardiomyocytes

Haydar S, Bednarz R, Laurette P, Sobitov I, Diaz i Pedrosa N, Videm P, Lüneburg T, Kuss S, Lahm H, Dressen M, Krane M, Schmidt C, Grüning BA, Voigt N, Streckfuss-Boemeke K & Gilsbach R.

Nature Commun. Nat Commun 17, 117, 2026

view publication
2026

Cardiac Epigenome in Heart Development and Disease.

Laurette P & Gilsbach R.

Nature Reviews Cardiology. 2026

view publication
2025

Transcriptional signature of cardiac myocyte recovery in mice and human reveals persistent upregulation of epigenetic factors.

Roth R, Hackh M, Schnick T, Rommel C, Koentges C, Bugger H, Domisch C, Bristow MR, Ambardekar AV, McKinsey TA, Gilsbach R*, Hein L* & Preissl S*.

Epigenetics. 20:2506625, 2025.

view publication
PubMed Publications

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